Buffalo Bills host the Miami Dolphins in Thursday Night Football as Week 3 opens, with Buffalo riding a 2-0 start and Miami slumping 0-2. Bills are the heavy -13.5 favorite, and the slate features two undefeateds in Philly vs Los Angeles and Arizona vs San Francisco. Giants vs Chiefs caps Sunday Night, while Lions visit Ravens on Monday Night Football. The full card lists every Week 3 game with lines, totals, and FPI odds to guide fantasy lineups and bold bets.

Fantasy emphasis centers on exploiting high-scoring expectancies and favorable game scripts. Track line moves and totals for starts like top offenses and potential shootouts, while identifying mid-range sleepers in games with clear target volume or pace advantages. Use the odds and projections to balance upside with risk as Week 3 decisions tighten.

Mac Jones stepped in for a sidelined Brock Purdy and threw for 279 yards with 3 TDs in a 26-21 win that pushed the 49ers to 2-0. The performance ignited a flood of “what if” takes across outlets, pitting Jones against Trey Lance and sparking Montana–Young comparisons. Jones flashed upside, though the opponent was Saints-draped by a shaky last-year yardage tally. Purdy’s health looms large as San Francisco weighs its long-term QB path.